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Assays involving inhibitors or inducers of these two signaling pathways revealed that Nrf2 and NF-κB activation was essential for LPS-induced GSS upregulation

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( Due to the increase of the senior population in recent years, age-related diseases such as neurodegenerative diseases have become more common and pose a serious threat to human health ( Therefore, we conducted a systematic review of research articles on the role of berberine in neurodegenerative diseases over the past decade